results of pethidine on other medicines Pethidine antagonize results of domperidone and metoclopramide on gastro-intestinal activity.
Aktiv substans: Ospecificerad substans (för licens- och extemporeläkemedel) ATC-kod: N02AB02 fileör details om det avregistrerade läkemedlet omfattas av Läkemedelsförsäkringen, kontakta Läkemedelsförsäkringen. Bipacksedel
Avoid or Use Alternate Drug. Concomitant therapy must be discontinued instantly if indications or signs or symptoms of serotonin syndrome arise and supportive symptomatic procedure needs to be initiated. .
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Reserve concomitant prescribing of such medicines in people for whom other therapy solutions are insufficient. Restrict dosages and durations on the minimal required. keep track of carefully for signs of respiratory melancholy and sedation.
olanzapine/samidorphan will decrease the level or result of meperidine by pharmacodynamic antagonism. Contraindicated. Samidorphan elicits opioid antagonistic effects and will increase danger of precipitating acute opioid withdrawal in clients dependent on opioids.
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Linezolid could boost serotonin on account of MAO-A inhibition. If linezolid must be administered, discontinue serotonergic drug right away and monitor for CNS toxicity. Serotonergic therapy may very well be resumed 24 hrs after very last linezolid dose or after two months of checking, whichever comes first.
Danish writer Tove Ditlevsen experienced a lifelong addiction to pethidine soon after her partner, a health care provider, had injected her with Demerol for a painkiller for an illegal abortion in 1944.[48]
Samtidig användning av Petidin Meda och läkemedel såsom barbiturater, bensodiazepiner eller andra CNS-depressiva läkemedel (som andra opioider, lugnande läkemedel eller hypnotika, generella anestetika, fentiaziner, muskelavslappnande läkemedel, lugnande antihistaminer) eller liknande läkemedel kan leda until sedering, andningsdepression, koma och död. På grund av dessa risker fileörbehålls samtidig fileörskrivning av opioider och barbiturater, bensodiazepiner eller andra CNS-depressiva läkemedel till patienter för vilka andra behandlingsalternativ inte är möjliga.
Antipsychotics extreme hypotension might arise when pethidine is administered to clients whose ability to maintain blood pressure level has been compromised by a depleted blood quantity or from the administration of medicines for instance phenothiazine.
For those who have been prescribed pethidine, but your pain is just not nicely controlled, or you may have any unforeseen Unwanted side effects, talk to your physician.
approach to administration Pethidine Injection may very well be administered by subcutaneous, intramuscular or gradual intravenous injection.
Prolonged use all through pregnancy may lead to neonatal opioid withdrawal syndrome, which can be website existence-threatening if not regarded and dealt with, and requires administration As outlined by protocols formulated by neonatology experts